Interstate 35 triumphed over Clarke 37-0 on Friday night in their second game of the season.
The Roadrunners established a 7-0 lead in the first quarter and never let Clarke close enough to score.
Two passing touchdowns and one rushing were scored by Jace Bedwell. Nick Steinlage scored two rushing touchdowns. Dustin George scored one receiving touchdown.
Interstate 35 finished with 294 yards rushing and 168 passing.